Proteins with Stoke’s Radius About 6 Nm are Excluded

Question

Proteins with Stoke’s radius > about 6 nm are excluded from the ultrafiltrate because
A) They are too large to fit through pores in the endothelium
B) They have too many negative charges and are repelled by the negative basement
mem brane
C) They move too slowly
D) They are too large to fit through pores in the slit diaphragms
E) This is not true. Proteins with Stokes radius > 6 nm still end up in the ultrafiltrate

Accepted Answer

Proteins with a Stokes radius greater than about 6 nm are too large to pass through the pores in the slit diaphragms of the glomerular filtration barrier, preventing them from entering the ultrafiltrate.