CRH Directly Stimulates

Question

CRH directly stimulates
A) ACTH secretion by activating a Gs-coupled receptor on corticotropes
B) TSH secretions by activating a Gq- coupled receptor on thyrotropes
C) GH secretion by activating a Gs-coupled receptor on somatotropes
D) Cortisol secretion
E) Aldosterone secretion

Accepted Answer

CRH (Corticotropin-Releasing Hormone) directly stimulates ACTH (Adrenocorticotropic Hormone) secretion by activating a Gs-coupled receptor on corticotropes in the anterior pituitary. This leads to the production and release of ACTH, which then acts on the adrenal cortex to stimulate cortisol production.