In a Synthetic Lethal,which of the Following Phenotypes is Most

Question

In a synthetic lethal,which of the following phenotypes is most likely to be non-viable? A) A⁺B⁺ B) A^-B⁺ C) A⁺B^- D) A^-B^- E) A⁺A^-B⁺ B⁺

Accepted Answer

In a synthetic lethal interaction, the loss of one gene is only lethal when combined with the loss of a second gene. Therefore, the genotype A^-B^- is most likely to be non-viable as it has lost both genes in the synthetic lethal pair, while the other genotypes have either retained both genes or lost only one of the genes in the synthetic lethal pair.