Which of the Following is Most Likely to Produce a Chromosomal

Question

Which of the following is most likely to produce a chromosomal inversion?
A) aneuploidy
B) one double-strand breakage on each of two different chromosomes
C) transposition of a retrotransposon
D) double-strand breakage at two positions on the same chromosomes
E) Robertsonian translocation

Accepted Answer

Double-strand breakage at two positions on the same chromosome can result in the inversion of the segment between the break points. The other options do not typically lead to chromosomal inversions. Aneuploidy refers to the gain or loss of individual chromosomes, transposition of retrotransposons may affect the position of genes but does not lead to chromosomal inversions, and Robertsonian translocations involve the fusion of two acrocentric chromosomes and do not result in inversions.