Which of the Following Statements About CpG Islands is CORRECT

Question

Which of the following statements about CpG islands is CORRECT?
A) CpG islands are commonly found at the 3' UTR regions.
B) The CpG island methylation is universal across both prokaryotes and eukaryotes.
C) Methylated CpG islands are associated with long-term gene repression.
D) Transcriptionally active DNA has a higher frequency of methylated CpG.
E) There is an association between DNA methylation at the CpG island and acetylation of histone via recruitment of acetylases.

Accepted Answer

Methylated CpG islands are associated with long-term gene repression, as methylation can prevent transcription factors from binding and recruit proteins that compact chromatin.