Could the characteristic followed in the pedigree below be caused by an autosomal dominant disease? Why or why not?

A) Yes, all individuals fit the autosomal dominant inheritance pattern.
B) No, the offspring of I-1 and I-2 contradict an autosomal dominant inheritance.
C) No, the offspring of I-3 and I-4 contradict an autosomal dominant inheritance.
D) No, the offspring of II-3 and II-4 contradict an autosomal dominant inheritance.
E) Yes, the offspring of I-1and I-2 are consistent with an autosomal dominant inheritance pattern.