What Does the Hydrolysis of a Purine Base from the Deoxyribose-Phosphate

Question

What does the hydrolysis of a purine base from the deoxyribose-phosphate backbone leave behind?
A)an apurinic site
B)a modified base
C)a double-strand break
D)a mutation
E)a deletion

Accepted Answer

Hydrolysis of a purine base from the deoxyribose-phosphate backbone results in an apurinic site, which is a site in DNA that has lost a purine base (adenine or guanine). This can happen spontaneously or due to damage, leaving behind a gap where the purine base used to be.