The Complement Pathway That Requires Antibodies to Be Activated Is

Question

The complement pathway that requires antibodies to be activated is the
A) alternate pathway.
B) classical pathway.
C) properdin pathway.
D) inflammatory pathway.
E) lectin pathway.

Accepted Answer

The classical pathway is activated by the presence of antibodies, specifically IgM or IgG, that recognize and bind to an antigen. This binding triggers a series of enzymatic reactions that ultimately lead to the activation of complement proteins. The other pathways (alternate, properdin, lectin, and inflammatory) can be activated independently of antibodies.