The Normal Microbiota of the Genital Tract of Women Is

Question

The normal microbiota of the genital tract of women is
A) affected by estrogen levels.
B) dependent on the activity of Lactobacillus.
C) unchanging.
D) typically composed of Escherichia coli.
E) affected by estrogen levels AND dependent on the activity of Lactobacillus.

Accepted Answer

The normal microbiota of the genital tract of women is affected by estrogen levels as estrogen increases the glycogen content of the vaginal epithelium, which is then metabolized by Lactobacillus to produce lactic acid. This production of lactic acid helps to maintain an acidic vaginal pH, which prevents the growth of potential pathogens. Therefore, the normal microbiota is dependent on the activity of Lactobacillus.