Which of the Following Statements About Collagen is FALSE

Question

Which of the following statements about collagen is FALSE?
A)Collagen synthase organizes the mature collagen molecules into ordered collagen fibrils.
B)Collagen is synthesized as procollagen and secreted to the outside of the cell in a secretory vesicle.
C)The terminal procollagen domains are cleaved by a protease in the extracellular space.
D)Cells can break down a collagen matrix using matrix proteases.

Accepted Answer

Collagen synthase is not responsible for organizing mature collagen molecules into ordered collagen fibrils. Instead, this process involves various other enzymes and molecular interactions. The correct term for the enzyme involved in the formation of collagen fibrils is not "collagen synthase"; rather, enzymes like lysyl oxidase play a role in cross-linking collagen molecules, contributing to the formation and stabilization of collagen fibrils.