Question 7
(Multiple Choice)
You prepare bacterial cell extracts by lysing the cells and removing insoluble debris via centrifugation.These extracts provide the proteins required for DNA replication.Your DNA template is a small, double-stranded circular piece of DNA (a plasmid) with a single origin of replication and a single replication termination site.The termination site is on the opposite side of the plasmid from the origin. 
Figure 6-11
What part of the DNA replication process would be most directly affected if a strain of bacteria lacking the exonuclease activity of DNA polymerase were used to make the cell extracts?
A)initiation of DNA synthesis
B)Okazaki fragment synthesis
C)leading-strand elongation
D)lagging-strand completion
Answer