If a Cell Were Unable to Produce Histone Proteins, Which

Question

If a cell were unable to produce histone proteins, which of the following would be a likely effect?
A) The cell would immediately divide.
B) Spindle fibres would not form during prophase.
C) The cell's DNA couldn't be packed into its nucleus.
D) Amplification of other genes would compensate for the lack of histones.
E) There would be an increase in the amount of "satellite" DNA produced during centrifugation.

Accepted Answer

Histones are proteins that package DNA into structures called nucleosomes, which are the basic unit of chromatin. Without histones, DNA would not be able to be compacted and organized into chromosomes within the nucleus. This would lead to a lack of chromosomal organization and potentially affect gene expression and cell function.