Which of the following statements are true of the chemical regulation of respiration? (Read carefully and select all of the correct statement.)

A)The strongest stimulus to increase breathing is a decrease in CO₂ in the body fluids.
B)The carotid bodies and jugular body contain receptors that detect decreased oxygen.
C)Central chemoreceptors that are very sensitive to decreased CO₂ are located in the cerebrum.
D)Severe hypoxia will stimulate an increase in breathing rate and depth.