Allosteric Regulation Depends on Inhibitors Binding to the Active Site

Question

Allosteric regulation depends on inhibitors binding to the active site of enzymes.

Accepted Answer

Allosteric regulation involves effector molecules binding to a specific site on the enzyme, called the allosteric site, in order to either activate or inhibit enzyme activity. The allosteric site is distinct from the active site, where substrate molecules bind to undergo catalysis. Therefore, inhibitors do not bind to the active site in allosteric regulation.