What is the Initial Step in DNA Replication

Question

What is the initial step in DNA replication?
A) breakdown of the nuclear envelope
B) formation of the mitotic spindle
C) formation of the cleavage furrow
D) unwinding of the DNA double helix

Accepted Answer

The initial step in DNA replication is the unwinding of the DNA double helix to expose the two strands of the DNA molecule. This process is mediated by enzymes known as helicases. Once the DNA has been unwound, replication can proceed with the addition of complementary nucleotides to each of the separated strands.