Which Protein Modification is Most Closely Linked to Protein Degradation

Question

Which protein modification is most closely linked to protein degradation?
A)ubiquitination
B)phosphorylation
C)glycosylation
D)methylation
E)acetylation

Accepted Answer

Ubiquitination is a process by which a protein is tagged with ubiquitin molecules, which then signal for the protein to be degraded by the proteasome. Thus, ubiquitination is most closely linked to protein degradation.