Which of the Following Would Be LEAST Likely to Contribute

Question

Which of the following would be LEAST likely to contribute to transformation of a cell?
A)A mutation resulting in a change in splicing
B)A mutation in a transcription factor
C)A silent mutation in an intron
D)An activating mutation in an exon of a gene coding for a protein that promotes cellular proliferation
E)Changes in the expression level of a miRNA that is involved in protein synthesis

Accepted Answer

A silent mutation in an intron would not affect the final protein product or its function, so it would have the least contribution to transformation of a cell.