Which of the Following Scenarios Will NOT Result in an Increase

Question

Which of the following scenarios will NOT result in an increase in apoptotic activity?
A)Overexpression of Noxa
B)Inhibition of Bcl-2 signaling
C)Phosphorylation of Bim
D)Activation of caspase-9
E)Flux in cellular calcium levels

Accepted Answer

Phosphorylation of Bim often leads to its inactivation or degradation, which would not increase apoptotic activity but rather decrease it, as Bim is a pro-apoptotic BH3-only protein that promotes apoptosis when active.