The Complex Formed When a Steroid Hormone Binds to a Cytoplasmic

Question

The complex formed when a steroid hormone binds to a cytoplasmic receptor
A) must first be activated by an intracellular signaling cascade.
B) translocates to the nucleus.
C) translocates to the Golgi apparatus.
D) phosphorylates targets in the cytoplasm.
E) phosphorylates targets in the nucleus.

Accepted Answer

When a steroid hormone binds to a cytoplasmic receptor, the resulting complex translocates (moves) from the cytoplasm to the nucleus. Once in the nucleus, it can act as a transcription factor to regulate gene expression. There is no need for activation by an intracellular signaling cascade, phosphorylation of targets, or translocation to the Golgi apparatus.