The Major Class(es) of Antibiotics That Inhibit Protein Synthesis Is/are

Question

The major class(es) of antibiotics that inhibit protein synthesis is/are
A)aminoglycosides.
B)tetracyclines.
C)macrolides.
D)bacitracins.
E)aminoglycosides, tetracyclines AND macrolides.

Accepted Answer

Aminoglycosides, tetracyclines, and macrolides all inhibit bacterial protein synthesis by targeting different components of the translation machinery. Aminoglycosides bind to the 30S subunit and interfere with the formation of the initiation complex, tetracyclines bind to the 30S subunit and prevent binding of aminoacyl-tRNA, and macrolides bind to the 50S subunit and prevent elongation and translocation during protein synthesis. Bacitracins, on the other hand, inhibit cell wall synthesis by disrupting the formation of peptidoglycan. Therefore, the correct answer is E.