A patient has been receiving immunosuppressive doses of glucocorticoids for 6 months.At the end of this therapy,the dosage of the hormone must be slowly tapered down over a period of weeks.This is because of the development of:
A)Adrenal atrophy. B)Pituitary hypertrophy. C)Upregulation of glucocorticoid receptors. D)Elevated ACTH levels. E)Increased levels of circulating cortisol-binding globulin (CBG).