In the Male Hypothalamic-Pituitary-Gonadal Axis,negative Feedback on LH Secretion Is

Question

In the male hypothalamic-pituitary-gonadal axis,negative feedback on LH secretion is limited to:
A)Testosterone and estradiol.
B)Testosterone and DHT.
C)DHT and estradiol.
D)Testosterone,DHT,and inhibin.
E)Testosterone.

Accepted Answer

Testosterone and estradiol are the primary hormones involved in the negative feedback mechanism on LH (Luteinizing Hormone) secretion in the male hypothalamic-pituitary-gonadal axis. Testosterone produced by the testes and estradiol, which is a form of estrogen converted from testosterone, both play key roles in regulating LH levels to maintain hormonal balance.