Which of the following would most likely occur if an in vitro transcription assay is performed using a cell extract containing an alpha subunit without the C-terminal domain?
A)Polymerase would become tightly associated with the promoter. B)Polymerase would become more susceptible to proteolysis. C)Transcription will be accelerated. D)Polymerase complex would be loosely associated with the promoter. E)Recognition of the UP element would be faster.