Which of the Following is Most Likely to Occur If

Question

Which of the following is most likely to occur if the level of glucose is low in a bacterial cell?
A)Cyclic-AMP levels will be depressed.
B)CAP will assist in stimulating transcription of the lac operon.
C)CRP activity will be inhibited.
D)Both Cyclic-AMP levels will be depressed and CRP activity will be inhibited are correct.
E)None of the choices is correct.

Accepted Answer

When glucose levels are low in a bacterial cell, cyclic AMP (cAMP) levels increase. This cAMP binds to the catabolite activator protein (CAP), also known as CRP (cAMP receptor protein), enabling it to assist in stimulating transcription of the lac operon by facilitating the binding of RNA polymerase to the promoter.