Holliday Junctions are Intermediates in RecBCD Recombination in E.coli

Question

Holliday junctions are intermediates in RecBCD recombination in E.coli.

Accepted Answer

Holliday junctions are formed during the process of homologous recombination, which is facilitated in E.coli by the RecBCD enzyme complex. The Holliday junction is an intermediate structure that forms between two homologous DNA molecules as they are undergoing strand exchange. The junction is resolved by additional enzymes to yield recombinant DNA molecules.