Which of the Following is Not Necessary for Retroviral Insertion

Question

Which of the following is not necessary for retroviral insertion into the host genome?
A)RNA polymerase II
B)retroviral pol gene
C)viral protease
D)RNase H
E)reverse transcriptase

Accepted Answer

Retroviral insertion into the host genome requires the actions of retroviral pol gene-encoded enzymes, including reverse transcriptase (which copies viral RNA into DNA), RNase H (which degrades the RNA strand of the RNA-DNA duplex created by reverse transcriptase), and viral protease (which cleaves precursor viral proteins into their functional forms). RNA polymerase II is a host enzyme involved in transcription, but it is not directly required for retroviral insertion into the host genome.