Which of the Following Enzymes is Used to Search for CpG

Question

Which of the following enzymes is used to search for CpG islands?
A)EcoRI
B)HindIII
C)HpaII
D)PvuI
E)BamHI

Accepted Answer

The enzyme HpaII specifically targets and cuts DNA at sites where the cytosine is methylated in the CpG (cytosine-phosphate-guanine) dinucleotide sequence. Therefore, it can be used to search for CpG islands, which are regions of DNA with a high frequency of CpG sites. The other enzymes listed do not have a specific preference for CpG sites.